YANGI TUG'G'ILGAN BOLALARNING RESPIRATORIY DISTRS SINDROMINING GENETIK OMILLARI
Ключевые слова:
RDS - bu shoshilinch tibbiy yordamni talab qiladigan jiddiy holat. Xavf omillari va kasallikning tarqalishidagi mintaqaviy farqlarni tushunish samarali oldini olish va davolash strategiyalarini ishlab chiqishga yordam beradi. RDSni erta aniqlash va davolashning samaradorligini oshirish uchun xavf omillarini, jumladan, genetik va atrof-muhit omillarini tushunish juda muhimdir. Bu yangi tug'ilgan chaqaloqlarda nafas olish bilan bog'liq muammolarni kamaytirishga yordam beradi va uzoq muddatli asoratlarni oldini oladi.Аннотация
Respirator sindromi (RDS) yangi tug'ilgan chaqaloqlarda tug'ilgandan so'ng darhol paydo bo'ladigan nafas olish muammosidir. Bu neonatal intensiv terapiya bo'limiga yotqizish va yangi tug'ilgan chaqaloqlarda nafas olish etishmovchiligining eng keng tarqalgan sabablaridan biridir. O'pkada sirt faol moddalar etishmasligidan kelib chiqqan RDS, asosan, erta tug'ilgan chaqaloqlarda uchraydi, ammo to'liq muddatli chaqaloqlarda ham rivojlanishi mumkin. RDSga sezuvchanlikda genetik omillar muhim rol o'ynaydi. Elektron mikroskopiya va genetik testlar, jumladan SFTPB, SFTPC va ABCA3 genlarining ketma-ketligini o'rganish, RDSning molekulyar mexanizmlarini tashxislash va tushunishda foydali bo'lishi mumkin. RDS bilan yangi tug'ilgan chaqaloqlarda nafas olish natijalarini yaxshilash uchun genetik omillarni hisobga olish muhimdir, bu esa profilaktika va terapevtik tadbirlarni o'z vaqtida va etarli darajada amalga oshirish imkonini beradi. RDS prognozi kasallikning og'irligi va asosiy sababiga bog'liq
Библиографические ссылки
Horowitz K, Feldman D, Stuart B, Borgida A, Ming Victor, Fang Y, Herson V. // Full-term neonatal intenstive care unit admission in an urban community hospital: the role of respiratory morbidity. The Journal of Maternal-Fetal & Neonatal Medicine. 2011;24(11):1407–1410.
Gallacher D, Hart K, Kotecha S. // Common respiratory conditions of the newborn. Breathe. 2016;12(1):30–42.
Chalacon M, Debillon T, Plantaz D, Ego A. // Facteurs de risque de détresse respiratoire chez les prématurés modérés (32 à 34 semaines d’aménorrhée) [Internet] Médecine humaine et pathologie. 2012. Available from:
Shaili Amatya1, Meixia Ye, Lili Yang, Chintan K. Gandhi, Rongling Wu, Beth Nagourney and Joanna Floros. // Single Nucleotide Polymorphisms Interactions of the Surfactant Protein Genes Associated With Respiratory Distress Syndrome Susceptibility in Preterm Infants. // ORIGINAL RESEARCH published: 04 October 2021 Frontiers in Pediatrics
Qian L, Liu C, Guo Y, et al. // Current status of neonatal acute respiratory disorders: a one-year prospective survey from a Chinese neonatal network. Chin Med J (Engl) 2010;123:2769–2775
Jian Wang, Xuehua Liu, Tong Zhu, Chaoying Yan. // Analysis of neonatal respiratory distress syndrome among different gestational segments. Int J Clin Exp Med. 2015;8(9):16273–16279
Bouziri A, Ben Slima S, Hamdi A, et al. // Acute respiratory distress syndrome in infants at term and near term about 23 cases. Tunis Med. 2007;85:874–879.
Nagendra, K., Wilsom, C.G., Ravichander, B., Sood, S., Singh, S.P. (2017).
Ghafoor T, Mahmud S, Ali S, Dogar SA. // Incidence of respiratory distress syndrome. Journal of the College of Physicians and Surgeons, Pakistan : JCPSP. 2003;13(5):271–273
Bakr A, Abbas M. // Severe respiratory distress in term infants born electively at high altitude. BMC Pregnancy and Childbirth. 2006;6 (1).
Reuter S, Moser C, Baack M. // Respiratory Distress in the Newborn. Pediatrics in Review. 2014;35(417)/
Hansen, A.K., Wisborg, K., Uldbjerg, N., Henriksen, T.B. (2008).
Jing Liu, Na Yang, Ying Liu. // High-risk Factors of Respiratory Distress Syndrome in Term Neonates: A Retrospective Case-control Study. Balkan Med J. 2014;31(1):64–68.
Anatolyevna B. S., Muinovna K. F. Morphofunctional relationships of cells in the bronch in chronic inflammation //The American Journal of Medical Sciences and Pharmaceutical Research. – 2023. – Т. 5. – №. 06. – С. 100-104.
Авагимян А. А. и др. Сравнительная характеристика кардиопротекторных эффектов дапаглифлозина и триметазидина на модели доксорубицин-циклофосфамидной кардиотоксичности //Инновационная медицина Кубани. – 2023. – №. 4. – С. 6-14.
MUINOVNA K. F. et al. THE IMPORTANCE OF MARKERS CK7 AND TTF-1 IN METASTATIC LUNG TUMORS //JOURNAL OF BIOMEDICINE AND PRACTICE. – 2023. – Т. 8. – №. 3.
Kumar A, Bhat BV. // Epidemiology of respiratory distress of newborns. Indian journal of pediatrics. 1996;63(1):93–98.
Fedakar A, Aydogdu C. // Clinical features of neonates treated in the intensive care unit for respiratory distress. The Turkish journal of pediatrics. 2011;53(2):173–179
Abdelrahman SM, Hamed SM, Nasr A. // Neonatal respiratory distress in Omdurman Maternity Hospital, Sudan. Sudanese journal of paediatrics. 2014;14(1):65–70
Rubaltelli FF, Dani C, Reali MF, et al. // Italian Group of Neonatal Pneumology. Acta paediatrica. 12. Vol. 87. Oslo, Norway: 1992. Acute neonatal respiratory distress in Italy: a one-year prospective study; pp. 1261–1268. 1998
Mikko Hallman, Ritva Haataja. // Frontiers in Bioscience 12, 2670-2682, January 1, 2007] 2670 Genetic basis of respiratory distress syndrome
Gao Y, Li J. //Significance of combined application of biomarkers in the diagnosis and prognosis assessment of patients with acute respiratory distress syndrome. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2021 Jan;33(1):69-73. Chinese.
Д.Ю. Овсянников, Е.В. Бойцова, М.А. Жесткова, И.В. Кршеминская, И.К. Ашерова, С.Е. Украинцев, С.С. Межинский. НЕОНАТАЛЬНАЯ ПУЛЬМОНОЛОГИЯ. Монография Под редакцией Д.Ю. Овсянникова Москва 2022 СТР.168
Hamidova F. Methodology of Organizing the Stage of Training Lexical Units //Journal of Language Pedagogy and Innovative Applied Linguistics. – 2024. – Т. 2. – №. 3. – С. 11-15.
Исмоилов Ж. М. и др. СТРУКТУРНОЕ КОМПОНЕНТЫ СТЕНКИ БРОНХИАЛЬНОГО ДЕРЕВО И ИХ ГИСТОГЕНЕЗ И ВОЗРАСТНЫЕ ИЗМЕНЕНИЕ (обзор литературы) //Научный Фокус. – 2024. – Т. 1. – №. 12. – С. 460-471.
Muinovna X. F. et al. CHARACTERISTICS OF CHANGES IN THE NERVOVASCULAR SYSTEM IN THE NECK REGION DURING HANGING ON THE STRANGULATION LOOP (LITERATURE REVIEW) //Научный Фокус. – 2024. – Т. 1. – №. 11. – С. 478-484.
Журавлева Л.Н., Новикова В.И. // Определение концентрации сурфактантного белка d в сыворотке крови и трахеобронхиальном секрете при респираторном дистресс-синдроме и врожденной пневмонии у недоношенных новорожденных // Вестник ВГМУ. 2019.
Овсянников Д.Ю., Жесткова М.А., Стрельникова В.А., Аверин А.П и др. ГЕНЕТИЧЕСКИЕ ДИСФУНКЦИИ СИСТЕМЫ СУРФАКТАНТА У ДЕТЕЙ: РЕЗУЛЬТАТЫ МНОГОЦЕНТРОВОГО ИССЛЕДОВАНИЯ // Доктор.Ру. 2023. №3.
Муиновнa Х. Ф. и др. PОЛЬ ПЛAЦЕНТЦИТА В ВОЗНИКНОВЕНИЕ ВPОЖДЕННОЙ ПНЕВМОНИИ У НЕДОНОШЕННЫХ НОВОPОЖДЕННЫХ //IMRAS. – 2024. – Т. 7. – №. 1. – С. 486-492.
Muinovna K. F., Mardonovich I. J. Nonspecific and specific factors of bronchopulmonary tissue in inflammatory pathology //Journal Of Biomedicine And Practice. – 2023. – Т. 8. – №. 2.
