EFFECTIVENESS OF PREVENTIVE USE OF VITAMIN D IN YOUNG CHILDREN
Keywords:
children, vitamin D, vitamin D status, calcidiol, 25(OH)D, prevention of hypovitaminosis D.Abstract
75 children aged from 1 to 12 months were examined. life. During the period of minimal insolation, vitamin D deficiency was detected in more than half of young children (58.3%). Without drug prevention of hypovitaminosis D, the level of 25(OH)D in the blood serum of infants was 8.7 (6.3 - 14.8) ng/ml, which was significantly higher than with artificial feeding, a low level of 24.55 (19.0 - 32.0) ng/ml. ml. It has been established that taking cholecalciferol preparations in a prophylactic dose (500-1500 IU per day) significantly increases the supply of vitamin D to children, regardless of the nature of the diet.
References
Zakharova I.N., Dmitriyeva Yu.A., Vasilyeva S.V. et al. What pediatrician should know about vitamin D: new data on his role in an organism (part 1). Pediatriya 2014; 93: 3: 111–117. (in Russ.)
Zakharova I.N., Yablochkova S.V., Dmitrieva Yu.A. Well-known and indeterminate effects of vitamin D. Voprosy sovremennoj pediatrii 2013; 12: 2: 20–25. (in Russ.)
Muuns C., Zacharin R., Rodda C.P. et al. Prevention and treatment of infant and childhood vitamin D deficiency in Australia and New Zealand: a consensus statement. MJA 2006; 185: 268–272.
Black L.J., Seamans K.M., Cashman K.D. et al. An updated systematic review and meta-analysis of the efficacy of vitamin D food fortification. J Nutr 2012; 142: 1102–1108.
Calvo M.S., Whiting S.J. Survey of current vitamin D food fortification practices in the United States and Canada. J Ster Biochem Mol Biol 2013; 136: 211–213
Gromova O.A., Torshin I.Yu. Vitamin D – paradigm shift. Moscow: TORUS PRESS, 2015; 464. (in Russ.)
Maltsev S.V. Assessment of security with vitamin D of children and teenagers. Pediatriya 2014; 93: 5: 32–38. (in Russ.)
Holick M.F. Vitamin D: extraskeletal health. Rheum Dis Clin North Am 2012; 5: 95–105. 24. Heaney R.P., Davies K.M., Chen T.C. et al. Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol. Am J Clin Nutr 2003; 77: 204–210.
Holick M.F., Chen T.C. Vitamin D deficiency: a worldwide problem with health consequences. Am J Clin Nutr 2008; 87: 4: 1080–1086.
Bischoff-Ferrari H.A., Giovannucci E., Willett W.C. et al. Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes. Am J Clin Nutr 2006; 84: 1: 18–28.